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Apart from mitogenic, motogenic, and morphogenic properties, c-MET also protects against apoptosis by its interaction with PI3K/AKT (phosphatidylinositol 3-kinase/protein kinase-B) pathway

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However, these experiments revealed significantly elevated circulating levels of IL‐6 and IL‐10 within the first 24–48 h post‐injury in animals with combined injuries compared to those with isolated TBI [309, 310]